UV Spectrophotometric Method for Estimation of Moxifloxacin HCl in Tablet Dosage Form and Comparative Study of its Different Brands
An accurate and economical spectrophotometric method for the estimation of Moxifloxacin HCl in tablet dosage form has been developed and validated. The comparative studies of its different brands were assessed through evaluation of official and non official standards such as disintegration and dissolution with the specification of US pharmacopeia. The proposed developed method was based on the UV absorbance, 0.1 M HCl used as a solvent. In this method Moxifloxacin shows wavelength maxima at 294nm and method was validated as per ICH guidelines for linearity, precision and accuracy. This proposed method was successfully applied for the analysis of different brands of Moxifloxacin tablets available in the market and recovery study also revealed that there was no interaction occurred from the excipients present in the tablet.
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