Comparative Study of Effectiveness and Safety of Herbal Compound Medicine (Constinil) and Allopathic Medicine (Sodium Picosulfate) in Managing Constipation.

  • Mohammad Ishaque Mujeeb University of Balochistan, Sariab road, Quetta, Pakistan.
  • Piriha Abbasi ISRA University Hyderabad, Sindh, Pakistan.
  • Muhammad Amjad chishti Hamdard University, Karachi, Pakistan
Keywords: Constipation, effectiveness and safety of herbal Medicine.


Background:This present study was conducted to observe the effectiveness and safety of the herbal compound medicine (constinil) and allopathic medicine (sodium picosulfate) in managing the constipation. The functional constipation is a condition which can be described by evacuation of small quantity of feces, may be irregular, infrequent evacuation, hard and forceful pass stool, may defecation occur off/on pattern, delay in defecation once after 48-72 hours.

Methods: It was comparative case control study conduct on 110 from Oct-2014 to May-2015 at Hyderabad and Sehwan Sharif, Sindh. Patients only male gender (age between 20-50 years) with clinical diagnosis of functional constipation. Analysis was done by SPSS v20.

Results: this study show significant difference in post-treatment of between both groups (test and control group), signs and symptoms and duration of constipation. majority n=56, (91%) belong to hard stool, & feeling of evacuation complaints, n=14 (25%)  out of n=56 belong test group and n=42 (75%) belong to control group P 0.014.

Conclusion: Hence it is concluded constipation manage with herbal formulated capsule (constinil) is safer and effective.


Author Biographies

Mohammad Ishaque Mujeeb, University of Balochistan, Sariab road, Quetta, Pakistan.

Department of Eastern medicine, Faculty of Pharmacy, 

Piriha Abbasi, ISRA University Hyderabad, Sindh, Pakistan.

Department of Anatomy, Basic medical Sciences, 

Muhammad Amjad chishti, Hamdard University, Karachi, Pakistan

Department of basic medical sciences, Faculty of eastern medicine,