Burden of Syndrome X Among Females in Karachi, Pakistan

  • Zuneera Akram Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Muzammil Hussain Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Sadaf Ibrahim Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan
  • Mariam Razzak Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Rehana Perveen Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Aisha Noreen Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Zobia Zia Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Abstract

Aim: The co-relation of hypertension with hyperglycemic indicates the allocation of a common physiologic predecessor, suggested to be insulin tissue resistance. Insulin resistance is associated with a number of risk factors, identified and acknowledged as a metabolic syndrome or Syndrome X. Syndrome X is a term instead of a disease itself, used to emphasize determinants that increases the possibilities of cardiovascular disorders to approximately 2 times and for type II diabetes to 5 times.


Objective: The main objective of this study is to estimate the risk of Syndrome X among the females of Pakistan as well as the suggestions to control the spreading of the syndrome through advising proper lifestyle changes.


Methods: A random sampling method was used to do population-based cross-sectional study among 150 out of 280 women aged 35-55 years. Pregnant female and those who didn’t fast for 8-12 hours were excluded from all analyses. The data was obtained via percentage system.


Results: The national survey conducted implied that the metabolic syndrome is now very common in Pakistan, affecting about 30.66% and 56% (based on classification of amended guidelines of NCEP, and IDF respectively) of female population of age group of 35-55 years, being more common in women than above age of 50 years.


Conclusions: Syndrome X spread because of age factor and obesity as well as due to diabetes type II, hypertension and dyslipidemia. Adding exercise and diet to instigate weight loss in life the foundation of treatment. Atherogenic dyslipidemia, hypertension, and hyperglycaemia are treated with pharmacological involvement.

Author Biographies

Zuneera Akram, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology

Muzammil Hussain, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology

Sadaf Ibrahim, Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan

Department of Pharmacology, 

Mariam Razzak, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology, 

Rehana Perveen, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology, 

Aisha Noreen, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmaceutical Chemistry, 

Zobia Zia, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology, 

Published
2018-11-23
How to Cite
AKRAM, Zuneera et al. Burden of Syndrome X Among Females in Karachi, Pakistan. RADS Journal of Pharmacy and Pharmaceutical Sciences, [S.l.], v. 6, n. 3, p. 178-184, nov. 2018. ISSN 2521-8484. Available at: <http://jpps.juw.edu.pk/index.php/jpps/article/view/239>. Date accessed: 18 jan. 2019.
Section
Articles