Burden of Syndrome X Among Females in Karachi, Pakistan

  • Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan
  • Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
  • Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan
Keywords: Hypertension, hyperglycaemia, insulin tissue resistance, metabolic syndrome

Abstract

Aim: The co-relation of hypertension with hyperglycemic indicates the allocation of a common physiologic predecessor, suggested to be insulin tissue resistance. Insulin resistance is associated with a number of risk factors, identified and acknowledged as a metabolic syndrome or Syndrome X. Syndrome X is a term instead of a disease itself, used to emphasize determinants that increases the possibilities of cardiovascular disorders to approximately 2 times and for type II diabetes to 5 times.

Objective: The main objective of this study is to estimate the risk of Syndrome X among the females of Pakistan as well as the suggestions to control the spreading of the syndrome through advising proper lifestyle changes.

Methods: A random sampling method was used to do population-based cross-sectional study among 150 out of 280 women aged 35-55 years. Pregnant female and those who didn’t fast for 8-12 hours were excluded from all analyses. The data was obtained via percentage system.

Results: The national survey conducted implied that the metabolic syndrome is now very common in Pakistan, affecting about 30.66% and 56% (based on classification of amended guidelines of NCEP, and IDF respectively) of female population of age group of 35-55 years, being more common in women than above age of 50 years.

Conclusions: Syndrome X spread because of age factor and obesity as well as due to diabetes type II, hypertension and dyslipidemia. Adding exercise and diet to instigate weight loss in life the foundation of treatment. Atherogenic dyslipidemia, hypertension, and hyperglycaemia are treated with pharmacological involvement.

Author Biographies

, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology

, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology

, Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan

Department of Pharmacology, 

, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology, 

, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology, 

, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmaceutical Chemistry, 

, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan

Department of Pharmacology, 

Published
2018-11-23
Section
Articles