Impact of Physical Activity on Fasting, Random Blood Sugar and HbA1C in Type – II Diabetic Patients

Mahmood Sheikh; Sheikh Abdul Khaliq; Iqbal Azhar; Ejaz Mohiuddin

doi:10.37962/jpps.v8i2.363

Mahmood Sheikh Department of Pharmacognosy, Faculty of Pharmacy & Pharmaceutical Sciences, University of Karachi, Pakistan
Sheikh Abdul Khaliq Department of Pharmacy Practice and Pharmaceutics, Faculty of Pharmacy, Hamdard University, Karachi, Pakistan
Iqbal Azhar Department of Pharmacognosy, Faculty of Pharmacy & Pharmaceutical Sciences, University of Karachi, Pakistan
Ejaz Mohiuddin Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan

DOI: https://doi.org/10.37962/jpps.v8i2.363

Keywords: Exercise, Diabetes mellitus, blood sugar, HbA1C, glycemic control

Abstract

Objective: Aim of the study is to evaluate the impact of physical activities on fasting, random blood sugar and HbA1C on patients getting treatment with different systems of medicine.

Methods: Prospective cross sectional study was conducted in outpatient facilities of Karachi from July 2017 to July 2018 with treatment duration of at least one year. 195 type – II Diabetic patients with confirm diagnosis enrolled in the study. Study has three arms of anti-diabetic treatment; herbal, homeopathic and allopathic. Outcome measures are Fasting Blood Sugar (FBS), Random Blood Sugar (RBS) and HbA1C with and without exercise.

Results: In exercise group, mean reduction of FBS in patients; Allopathic=138.31±46.11 mg/dl, homeopathic=100±00 mg/dl, herbal=121.11±19.64 mg/dl, combination=135.20±40.85 mg/dl. Mean reduction of RBS; Allopathic=186.25±58.77 mg/dl, homeopathic=140.00±00 mg/dl, herbal=198.88±49.60 mg/dl, combination=231.90±64.10 mg/dl. Mean reduction of HbA1C; Allopathic=7.53±1.97%, herbal=6.47±0.335%, combination=7.21±1.147%. In patients not doing exercise, mean reduction of FBS in patients; Allopathic=183.80±85.49 mg/dl, homeopathic=119.00±47.71 mg/dl, herbal=131.00±17.68 mg/dl, combination=134.37±49.88 mg/dl. Mean reduction of RBS; Allopathic=240.08±92.76 mg/dl, homeopathic=163.00±32.33 mg/dl, herbal=193.66±46.42 mg/dl, combination=212.67±87.21 mg/dl. Mean reduction of HbA1C; Allopathic=8.89±2.04%, homeopathic=6.40±00%, herbal=6.54±0.398%, combination=7.10±1.53%. FBS is significantly better controlled by allopathic system compare to homeopathic (p=0.004), herbal (p=0.0001), combination (p=0.0001). RBS is significantly better controlled by allopathic system compare to homeopathic (p=0.006), herbal (p=0.017). Homeopathic system significantly better control RBS compare to combination treatment (p=0.036).

Conclusion: Physical activities and exercises can provide better control on FBS, RBS HbA1C. Allopathic and combination systems of medicine have better glycemic control in type – II Diabetes Mellitus patients involve in physical activities.