Ivy Herbal Products for Cough and its Validation for Hederacoside C Biomarker Determination with HPLC _PAD Techniques
Abstract
Different pharmaceutical companies in Pakistan have started production of high quality Ivy natural medicines for the cure of cough. Three different brands of Ivy syrup were evaluated for Hederacosides C biomarker with high-performance liquid chromatographic method coupled with a photodiode array detector. Good linear relation was observed through regression analysis (correlation coefficient 0.9994) between peak concentration the peak area. and limits of detection (LOD) and quantitation (LOQ) were 0.011 and 0.032 mg/mL, respectively, and percentage recovery was in the range of 99.69% to 100.90% (RSD < 2%)