Methods of Analysis of Vitamin K: A Review
Abstract
Vitamin K1 (phylloquinone) and K2 (menaquinone) are available in nature and K3 (menadione) is a man–made vitamin. They perform many physiological functions in humans. Several analytical methods are available for the determination of vitamin K including spectrometric, fluoriemetric, HPLC, electrochemical and microbiological methods. These methods have been applied to the assay of K vitamin in food, pharmaceuticals and biological fluids. The fluorimetric methods are more sensitive than the other methods. The details of these methods are reviewed in this article.