Incidence of Nephrotic Syndrome in Type 2 Diabetic Patients Presenting with Proteinuria

  • Ammad Masood Department of Medicine, Bahaw1Department of Medicine, Bahawal Victoria Hospital, Bahawalpur, Pakistanal Victoria Hospital, Bahawalpur, Pakistan
  • Sana Ujala Department of obstetrics and Gynecology, Bahawal Victoria Hospital, Bahawalpur, Pakistan
  • Syed Adil Ali Department of Medicine, Bahawal Victoria Hospital, Bahawalpur, Pakistan
Keywords: Diabetes mellitus Type 2, proteinuria, nephrotic syndrome


Background: Proteinuria in diabetic patients is usually interpreted as a clinical manifestation of diabetic nephropathy (DN). However, not all diabetic subjects with proteinuria have DN. Nondiabetic renal disease (NDRD) has been seen to cause proteinuria in diabetic patients. There is a wide variation of prevalence of NDRD. We conducted this study to determine the frequency of nephrotic syndrome in type 2 diabetic patients presenting with proteinuria.

Methodology: This study was a descriptive, cross-sectional study, conducted at department of Medicine, Bahawal Victoria Hospital, Bahawalpur. Total 92 individuals with type 2 diabetes between 30 and 60 years of age were enrolled in the study. Individuals with hypertension, chronic renal failure (CRF) and obstructive uropathy were excluded from the study. All individuals with nephrotic syndrome (presence/absence) were examined with appropriate medical history (diabetes duration, diabetes mellitus (DM) treatment, family history of kidney disease).

Results: The age group of this study was 30 to 60 years old, with an average age of 46.52 ± 7.23 years old. Most of the 53 patients (67.61%) were 51 to 60 years old. Among the 92 patients, 48 ​​were male (52.17%) and 44 were female (47.83%). The average BMI was found to be 27.41 ± 2.74 kg / m². Nephrotic syndrome was found in 37 (40.22%) patients, while 55 (59.78%) had no nephrotic syndrome.

Conclusion: Our study concluded that the incidence rate of nephrotic syndrome is high in individuals with type 2 diabetes.