Quality control of polyherbal drugs for the detection of microbial agents
Objective: Herbal drugs have been utilized for the treatment of infectious diseases as medicines since ancient times. Plant and their extracts used for the manufacturing of different dosage form design. Medicinal plant is comprised of different parts that include root, leaf, stem, flowers, bark that have a high level of microorganisms, bacteria, yeast and especially fungal molds.
Methods:The antimicrobial analysis conducted on herbal raw materials, Bulk, Extracts, we found less CFU/gm. and percentages of Total Aerobic Count in bulk and extracts because these are heated at extreme temperatures.
Results: We have observed no fungal growth in bulk and extracts so it is devoid of any spore and toxin formation. In Raw materials, some molds were found that is similar with nonpathogenic strain that will not produces any toxin. It is understood, if the toxin producing mold growth is present in raw materials so the herbs, extract and excipient when combined together and converted into bulk products, by this technique all the toxins and dormant spores are killed at an extreme temperature i.e. 18°F to 20°F. The bulk is the semi-finished product and combination of herbal raw materials, extract, and excipient after testing it will go for final packaging and we get the finished product. The supplier/manufacturer of raw materials will reveal its purity that is accepted or rejected by quality control (Microbiology and chemical lab), Herbion Pakistan (Pvt) Limited, Karachi, Pakistan.
Conclusion: It was concluded that PolyHerbal Drugs has effective and safe to consume for eradication of diseases.
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