Phytochemical Analysis and Tyrosinase Inhibitory Potential of Cassia absus (Seeds)

  • Saeed Ahmad The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Tayyeba Rehman The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Mariam Safdar The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Ayesha Hassan The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Abstract

Objective: To perform phytochemical analysis and investigation of the tyrosinase inhibitory activity of Cassia absus seeds.
Methods: Various extracts of Cassia absus seed were prepared such as ethanolic extract, n-hexane, chloroform, n-butanol and water fractions.  Tyrosinase inhibitory activity was performed using Kim’s methodology. The extracts were also subjected to phytochemical analysis.
Result: Phytochemical analysis showed presence of alkaloids, tannins, flavonoids, glycosides and saponins. Tyrosinase inhibition assay was performed for all the four fractions, n-butanol showed high activity of tyrosinase inhibition (86%) followed by crude ethanol extract (75%) and n. hexane (72%) and water (62%) as compared to kojic acid (97%).
Conclusion: From all the results, we found that that phytochemicals present in C. absus seed extract may be responsible for the tyrosinase inhibition activity. The data revealed C. absus seed extracts/fractions could be an addition to medicinal cosmetics.

Author Biographies

Saeed Ahmad, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Faculty of Pharmacy

Tayyeba Rehman, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Faculty of Pharmacy

Mariam Safdar, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Faculty of Pharmacy

Ayesha Hassan, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Faculty of Pharmacy

Published
2018-06-20
How to Cite
AHMAD, Saeed et al. Phytochemical Analysis and Tyrosinase Inhibitory Potential of Cassia absus (Seeds). RADS Journal of Pharmacy and Pharmaceutical Sciences, [S.l.], v. 6, n. 2, p. 127-131, june 2018. ISSN 2521-8484. Available at: <http://jpps.juw.edu.pk/index.php/jpps/article/view/219>. Date accessed: 17 oct. 2018.
Section
Articles