Evaluation of New Formulation (Verona X Tablet) in Patients with Erectile Dysfunction

Abstract

Introduction: Erectile dysfunction (ED)is highly prevalent affecting almost 50% of men in the 40-70 year age range especially in those who have co-morbidities like diabetes, atherosclerosis, hypertension etc. Over recent years, the use of complementary and alternative medicines has become increasingly popular, and ED is one condition for which herbal supplements are heavily promoted and easily accessible. Traditional herbs have been a revolutionary breakthrough in the management of ED and have become known worldwide as ‘instant’ treatment. Major progress has been made in this field and at present a number of herbs are identified as a sexual stimulator. This knowledge has led to the discovery of several new therapeutic targets and multiple medical approaches for the treatment of erectile dysfunction (ED). This research focuses on the combination of selected herb in the treatment of ED. Aim: To examine the effects of Verona X tablet therapy on ED using the five-item version of the International Inventory of Erectile Function (IIEF). Methods: In this multicenter, phase 2 trial, we collect 38 Subjects from different hospitals to receive Verona X tablet a 4-weeks treatment period. Subjects were instructed to take study drug twice a day; no restrictions were placed on food or alcohol intake. On 2nd and 4th weeks we take follow up and record the results. Main Outcome Measures: Improvement in erectile function (EF) was measured by International Index of Erectile Function (IIEF) questionnaire. Results:38 patients were selected for the multicenter clinical trial. Out of 38 patient 36 patients documented the improvement in ED. At the follow-up endpoint, Verona X tablet found to be effective and the tolerability was good. No adverse events were reported during the study period. Conclusion: The results from the current meta-analysis have suggested that Verona X is an effective and well-tolerated therapy for erectile dysfunction. The findings of the present research highlight the need for more efficient performance of higher quality, largesample, various-race, long-term, randomized controlled trials to verify the efficacy and safety of Verona X tablet.