Collagen and Collagenases: A Brief Review

  • Syeda Yamna Zia Baqai Medical University, Karachi, Pakistan
  • Sofia Ahmed Baqai Medical University, Karachi, Pakistan
  • Syed Abid Ali University of Karachi, Karachi-75270, Pakistan
  • Muhammad Ali Sheraz Baqai Medical University, Karachi, Pakistan
  • Iqbal Ahmad Baqai Medical University, Karachi, Pakistan
Keywords: Collagen, Collagenases, Dupytren’s contracture

Abstract

Collagen is the most important and abundant protein in the human body that is needed for a number of physiological functions such as tissue repair during wound and fracture healing. There are about thirty different types of collagen. Collagenases are enzymes that helps breakdown the deposited collagen in the muscles, joints, tissues and arteries. There are a variety of collagenases used in different dosage forms in the treatment of diseases such as wound healing, Dupytren’s contracture, Peyronie’s disease etc. A major part of the collagenase enzyme is used for the treatment of chronic wounds such as tumors, burns and ulcers.

Author Biographies

Syeda Yamna Zia, Baqai Medical University, Karachi, Pakistan

Baqai Institute of Pharmaceutical Sciences

Sofia Ahmed, Baqai Medical University, Karachi, Pakistan

Baqai Institute of Pharmaceutical Sciences

Syed Abid Ali, University of Karachi, Karachi-75270, Pakistan

H.E.J. Research Institute of Chemistry

Muhammad Ali Sheraz, Baqai Medical University, Karachi, Pakistan

Baqai Institute of Pharmaceutical Sciences

Iqbal Ahmad, Baqai Medical University, Karachi, Pakistan

Baqai Institute of Pharmaceutical Sciences

Published
2017-12-01