Toxicity Study of Infidol Colic Drop and Sennalax Administered Orally in NMRI Mice

Abstract

Objective: The present study was aimed to investigate preclinical oral toxicity of Infidol colic drop and Sennalax product.
Methods: NMRI strains of mice were selected for this study. Animals were divided into two groups i.e. control and treatment group (n=5/sex). Mice were treated orally using gastric gavage with doses (1 or 5 g/kg) of test product i.e. Infidol colic drops and sennalax, for 14 days and observed daily.
Result: The present study demonstrated that the infidol colic drops and sennalax is potentially safe with doses of 1000 & 5000 mg/kg, as it does not cause any apparent morbidity and mortality in the animals.
Conclusion: The test drug (Infidol colic drop and sennalax) could be safe because it did not show any of the side effects or toxicity on experimental animals.