Phytochemical Analysis and Tyrosinase Inhibitory Potential of Cassia absus (Seeds)

Abstract

Objective: To perform phytochemical analysis and investigation of the tyrosinase inhibitory activity of Cassia absus seeds.
Methods: Various extracts of Cassia absus seed were prepared such as ethanolic extract, n-hexane, chloroform, n-butanol and water fractions.  Tyrosinase inhibitory activity was performed using Kim’s methodology. The extracts were also subjected to phytochemical analysis.
Result: Phytochemical analysis showed presence of alkaloids, tannins, flavonoids, glycosides and saponins. Tyrosinase inhibition assay was performed for all the four fractions, n-butanol showed high activity of tyrosinase inhibition (86%) followed by crude ethanol extract (75%) and n. hexane (72%) and water (62%) as compared to kojic acid (97%).
Conclusion: From all the results, we found that that phytochemicals present in C. absus seed extract may be responsible for the tyrosinase inhibition activity. The data revealed C. absus seed extracts/fractions could be an addition to medicinal cosmetics.