Evaluation of Antipyretic Effects of Ultrahigh Dilutions of Baptisia tinctoria in Comparison with Paracetamol

  • Tayyeba Rehman
  • Saeed Ahmad
  • Waheed Mumtaz Abbasi
  • Aymen Owais Ghauri
  • Khalid Akhtar
  • Mohammad Bilal
  • Shifa Shafique
  • Mohammad Adeel Arshad
Keywords: Antipyretic, Baptisia tinctoria, homeopathy, ultrahigh dilutions

Abstract

Introduction: Homeopathy being an alternative treatment option has many controversies. The study aims to estimate the antipyretic effects of Baptisia tinctoria (200c and 1M ultrahigh dilutions) in animal fever model.

Methods: This study used Saccharomyces cerevisiae induced fever model. Animals were divided into 4 groups namely, negative control, positive control and Baptisia tinctoria 200c and 1M groups. During study, after each hour rectal temperature was checked. Paracetamol and homeopathic Baptisia tinctoria (200c and 1M) and paracetamol were given orally. One way statistical analysis was done with ANOVA followed by post hoc test. Significance level was p≤0.05.

Results: B. tinctoria in both potencies significantly reduced fever in rabbits compared to negative control group (p ≤ 0.05). At the end of study, paracetamol reduced by 2.5°F, while B. tinctoria 200c reduced by 1.7°F temperature and B. tinctoria 1M reduced by 1.9°F.

Conclusion: The study revealed that B. tinctoria showed its activity against fever, however, it has weaker action as compared to paracetamol.

Author Biographies

Tayyeba Rehman

University College of Conventional Medicine, Faculty of Pharmacy and Alternative Medicine, The Islamia

Saeed Ahmad

Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Waheed Mumtaz Abbasi

Medical and Health Division, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Aymen Owais Ghauri

Department of Eastern Medicine, Jinnah University for Women, Karachi, Pakistan

Khalid Akhtar

University College of Conventional Medicine, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Mohammad Bilal

First Department of Internal Medicine, University of Toyama, Toyama, Japan

Shifa Shafique

University College of Conventional Medicine, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Mohammad Adeel Arshad

Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Published
2019-07-31