Prognosis and the Global Impact of the COVID-19 Pandemic - A Comprehensive Review

  • Syeda Zainab Jinnah University for Women Karachi, Pakistan.
  • Syed Muhammad Farid Hassan University of Karachi, Karachi, Pakistan.
  • Rabia Noor University of Karachi, Karachi, Pakistan.
  • Farah Khalid Dow University of Health Sciences Karachi, Pakistan.
  • Monica Parkash J. Ojha University of Karachi, Karachi, Pakistan.
Keywords: COVID-19, SARS-CoV-2, Pandemic, Evolution, Pathogenesis, Treatment, Vaccine, Economy, Global Impact.


Background: The novel coronavirus 2019 or SARS-CoV-2 appeared first in the December, 2019, in the Wuhan, China. The virus later effected almost every part of the world.

Aim of the Review: The review is aimed to deliver a detailed prognosis of SARS-CoV-2 on basis of evaluation of different attributes of the virus reported or published.

Method: Articles were searched on Google Scholar and PubMed databases. All articles concerning SARS-CoV-2 were included. The duplicate articles were identified with EndNote and excluded. Related data from WHO, FDA and CDC were also included.

Results: The following parameters were found to show an important role in the prognosis of the SARS-CoV-2 i.e., physical properties, evolution, pathogenesis, epidemiology, demography, geography, diagnosis method, laboratory findings and clinical features. Moreover, several approaches were found to fight the viral infection including proposed therapies, proposed drugs, and vaccines. However, till the development of effective and safe approach the preventive measures are recommended to be strictly followed.

Conclusion: The global impact of this virus is beyond reconciliation and rapprochement. Its impact on various major industries such as agriculture, petroleum & oil, manufacturing industry, education and healthcare, and the pharmaceutical industries is inexplicable.

Review Article