Ivy Herbal Products for Cough and its Validation for Hederacoside C Biomarker Determination with HPLC _PAD Techniques

  • Zeeshan Ahmed Sheikh Herbion Pakistan (Pvt.) Ltd., Karachi, Pakistan
  • Aqib Zahoor Herbion Pakistan (Pvt.) Ltd., Karachi, Pakistan
  • Saleha Suleman Khan Herbion Pakistan (Pvt.) Ltd., Karachi, Pakistan
  • Safila Naveed Jinnah University for Women, Karachi
  • Syed Faisal Zaidi College of Medicine, King Saud bin Abdulaziz University of Health Sciences, Jeddah, Kingdom of Saudi Arabia
  • Khan Usmanghani Jinnah University for Women Karachi. Pakistan
Keywords: Ivy, Hedera helix, cough, hederacosides C, HPLC

Abstract

Different pharmaceutical companies in Pakistan have started production of high quality Ivy natural medicines for the cure of cough. Three different brands of Ivy syrup were evaluated for Hederacosides C biomarker with high-performance liquid chromatographic method coupled with a photodiode array detector. Good linear relation was observed through regression analysis (correlation coefficient 0.9994) between peak concentration the peak area. and limits of detection (LOD) and quantitation (LOQ) were 0.011 and 0.032 mg/mL, respectively, and percentage recovery was in the range of 99.69% to 100.90% (RSD < 2%)

Author Biographies

Safila Naveed, Jinnah University for Women, Karachi

Faculty of Pharmacy 

Syed Faisal Zaidi, College of Medicine, King Saud bin Abdulaziz University of Health Sciences, Jeddah, Kingdom of Saudi Arabia

Department of Basic Medical Sciences

Khan Usmanghani, Jinnah University for Women Karachi. Pakistan

Faculty of Pharmacy

Published
2015-06-02
Issue
Vol 3 No 1 (2015): Volume 3 (1) 2015
Section
Articles

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